Biological Age
29.4
3.6 years younger
The epigenetic test built for men
Because almost every testwas built on mixed data.
One saliva sample reads your hormone signals, your recovery and how fast you’re ageing, as a man. Ten reports, and a coach that learns you.
Scientific. Personal. Actionable.
18:55
95%
ST
DashboardPower Your Biology
Hey there, I’m EngneAI!
Ask me anything...
DNA ResultsSome of your DNA results
Epigenetic ResultsSome of your Epigenetic results
Recovery Score
86 /100
Optimal
Hormone Signals
Favourable
Testosterone / Cortisol
DNA Markers
285
CpG Site
The Problem
Your results came back normal. So why don’t you feel it? Because you’re not the average of a man and a woman, and half the signal calling you normal was never yours. Men age on a different clock, with different methylation, different hormones and a different pace entirely.
One average setting. Blind to every actual man.
AlphaAge reads your biology, not an average. Trained purely on male data, so the number it gives you is actually about you.
01The first epigenetic clock built on purely male data
0.88
R² on men.
285 CpG sites.
On women it drops to 0.77.
A blood test reads the moment. ENGNE reads the direction.
A BLOOD TEST | THE MOMENT
BIOLOGICAL AGE (SINGLE SNAPSHOT)
Markers
Result: 34.0
Static Data Panel
A snapshot on one random day, graded against a mixed-sex range. It catches what’s acutely wrong right now, and you should still get one.
SALIVA | ENGNE IS THE DIRECTION
Trend Vector: -2.1 units/yr|Retest Frequency: Tri-annual
BIOLOGICAL AGE
Retest 1Retest 2Retest 3Retest 4Retest 5TODAYFUTURE DIRECTION
TIME
The trend underneath it, read as a man and retested over time. Not what’s wrong today, but where your body is heading, and what moves it.
Follow the protocol, retest, and watch what moves.
Order & Test
Two minutes of saliva at your kitchen table. No needles, no clinic, no fasting. Post it back in the prepaid pack.
01
See Your Results
Your ten reports land in the ENGNE app around four to six weeks later, with a protocol built around your data.
02
Follow & Retest
Act on your data. Retest every quarter or six months and watch how your body responds.
03
01 / 03
WHAT YOU GET
Each one updates every time you retest. AlphaAge is the male-trained clock. Your DNA and epigenetic results sit underneath every number.
01· Flagship
AlphaAge
Biological age, pace of ageing, acceleration
02
Male Hormones
Testosterone and hormone signals
03
Performance
Muscle fibre type, VO₂ potential, recovery speed
04
Weight & Metabolism
Insulin sensitivity, fat distribution, appetite
05
Nutrition
Vitamin D, B12, folate, supplement priorities
06
Recovery
Sleep pressure, recovery rhythm, resilience
07
Heart & Longevity
Lipids, inflammation, vascular and longevity
08
Mind & Focus
Dopamine, serotonin, stress resilience, focus
09
Skin & Hair
Collagen turnover, skin ageing, hair health
10
Immunity & Inflammation
Immune resilience and inflammatory load
01 / 01
After your test you get your AlphaAge, your true male biological age. Not a verdict. A number you can move.
0.89x
pace
32
Your biological age
4.6 years younger than the calendar
Most health AI learned the internet and never met you. EngneAI reads your own DNA, epigenetics, goals and progress, then answers in plain language, from your MTHFR variant to your recovery load. It sharpens every time you retest, and it gets stronger every time someone new joins.
PERSONAL BIOLOGY INTERFACE
Hey there, I'm
EngneAI!
Ask about your body...
Not sure where to begin?Start with one of these:
Every clock before AlphaAge averaged male biology into mixed data. AlphaAge was rebuilt around men from the first signal.
01
Male biology standard
AlphaAge
Validated signal
The only clock built purely on male data.
0.88
R² on men
Male-trained biology
Yes
Epigenetic age
Yes
Age read from DNA
Yes
Androgen-linked loci
Yes
Pace of ageing
Yes
Horvath pan-tissueMixed-sex clock
No
Yes
Yes
Mixed
No
Pace-of-ageing clocksRate model
No
Rate only
No
Mixed
Yes
Wearable biological ageBehavioural estimate
No
No
No
No
No
MuhdoAgeConsumer DNA model
No
Yes
Yes
Yes
No
GlycanAgeImmune-age signal
No
Immune
Weak
Limited
No
AlphaAge is not a refinement. It is a male-first rebuild.
Signal comparison / 05
Five clinically formulated essentials, launching with every plan. Your reports and EngneAI then tune how you run them.
The five foundationsDaily baseline
01
Heart + brain
Foundation 01
Omega-3
Cardiovascular signal
02
Hormones + immunity
Foundation 02
Vitamin D3
Male hormone support
03
Recovery + sleep
Foundation 03
Tri-Magnesium
Three-form recovery
04
Thyroid + defence
Foundation 04
Selenium+
Cellular protection
05
Energy + focus
Foundation 05
B-Complex
Methylation support
01 / 05
Launching with every plan
Monthly from launch
One male baseline. Five foundations. Your data decides what changes next.
The test tells you where you are. Retesting is what tells you whether anything you changed worked.
Choose your feedback loop
Same science. Different retest cadence.
01 / 03
Full stack included
From launch, every subscription
Keep the app for life
Your data remains yours
Cancel after 3 months
Managed from the app
These men rely on ENGNE to read their biology exactly as it is. Their margins are too thin for a number that is only roughly right.
Male-first performance intelligence
4 champion profiles / verified members
ENGNE / 01
Champion profile
01
Jonathan Haggerty
ONE Kickboxing World ChampionTested withENGNE
ENGNE / 02
Champion profile
02
George Jarvis
WBC Muay Thai World ChampionTested withENGNE
ENGNE / 03
Champion profile
03
Sam Noakes
British & European ChampionTested withENGNE
ENGNE / 04
Champion profile
04
Nathaniel Wood
UFC Top 10Tested withENGNE
01 / 04
Powered by DEPH Labs
ENGNE is not a standalone product layer. ENGNE runs on the science, clinical thinking and platform team behind DEPH Labs.
The science & IP engine
Dr Saima Ajaz
CEO · DEPH LabsA physician-scientist at the frontier of metabolic and longevity medicine. Harvard-certified in lifestyle and nutritional medicine and a Diplomate of the American Board of Regenerative Medicine, she holds a PhD from King's College London, where she is Honorary Senior Clinical Lecturer. Across 20+ years at the Institute of Liver Studies, King's College Hospital, her research into mitochondrial bioenergetics and non-invasive biomarkers produced the patented biomarker panels at the core of DEPH's IP. She is Medical Director of the Harley Street Longevity Club and co-founder of UmmuHub.
Visit DEPH Labs
Clinical science layer
Biomarker architecture
Consumer platform & ownership layer
Lisa Loud
CEO · DEPH NetworkA proven operator who has scaled technology from inside the giants to the frontier of crypto. After Apple and PayPal, she went on to build and lead several multibillion-dollar blockchain protocols and networks, as CMO of BitMEX, COO of ShapeShift and a senior leader at Secret Network. Named to Forbes' Top 100, she now leads DEPH Network: the consumer platform and blockchain ownership layer that turns the science into something people own, control and are rewarded for.
Visit DEPH Network
Platform layer
Consumer execution
The team behind it
Research, product, brand, engineering and clinical performance — all moving through one system.
01 / 07
Christopher Collins
Chief Epigenetics OfficerArchitect of the sex-specific clocks and a published epigenetic-clock author, including a peer-reviewed saliva clock (DNA, 2025).
Aaron Hudson
Chief Technology OfficerLeads engineering across the apps, data platform and infrastructure.
Sam Thompson
Founder · Commercial DirectorIntegrates legal, brand, product, science and commercial into one engine.
Melody Maker
CMO · Creative DirectorOwns the brand, the story and the creative direction across DEPH.
Luke James
Sales DirectorDrives commercial growth, partnerships and clinical channel sales.
Dr Kennedy Obiekwe
Head of Sports MedicineTranslates the science into performance, recovery and longevity protocols.
Dr Mahd Siddiqi
Clinical Medicine · MedTechBridges frontline clinical practice with product and diagnostics.
Your data
Your biological data belongs to you. It is stored securely, encrypted, and never shared or sold without your explicit permission. Ever.
Nothing moves without your permission.
Partnerships & press
01 / 03
Before you start
Everything worth knowing before your first sample.
ENGNE preparation protocol
06 questions / testing / reports / AlphaAge / plans
Question index
06 entries
-
Still get bloods. They catch what’s acutely wrong today. But a blood draw is a snapshot on a random day, graded on a mixed-sex average. ENGNE reads the layer underneath, your epigenetics as a man, and tracks how fast you’re actually ageing over time.
-
One saliva sample unlocks ten living reports in the app, from AlphaAge and hormones to performance, recovery, heart and mind. Your DNA results and epigenetic results sit underneath, and EngneAI turns all of it into a plan.
-
Most health AI gives general advice. EngneAI uses your own DNA, epigenetic results, goals and progress, so it can answer things like whether your MTHFR variant means you should take methylation support.
-
On men, AlphaAge reads at R² 0.88 across 285 CpG sites, validated on independent male cohorts by our research team, which includes King’s College London clinical academics. On women it drops to 0.77, because it was built for men.
-
No needles. A simple saliva swab at home, posted back prepaid. Reports in around four to six weeks.
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Yes, any time after your 3-month minimum, straight from the app.
